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@#AIM: To investigate the efficacy of pars plana vitrectomy(PPV)with inner limiting membrane(ILMP)flap peeling and flute needle drawing in the treatment of idiopathic macular hole(IMH)without staining dye.<p>METHODS: A retrospective non-randomized case study on 76 patients(76 eyes)were diagnosed with IMH in our hospital from January 2018 to January 2019, 38 eyes were treated with PPV combined with ILMP and air tamponade without staining(group A), the remaining 38 eyes were treated with PPV combined with ILMP, needle drawing the Hole edge and air tamponde without staining(group B). The patients were followed up for more than 6mo, the macular hole closure, the best correct visual acuity(BCVA)and postoperative complication were analyzed in the two groups.<p>RESULTS: At 6mo after surgery, the closure rate of MH and BCVA improvement rate in group A were significantly lower than those in the group B(84% <i>vs</i> 100%, 76% <i>vs</i> 95%, <i>P</i><0.05). With the passage of postoperative time after surgery, the BCVA of two groups of patients gradually improved, and the BCVA of group B was better than that of group A at 7, 14d, and 1, 3, 6mo after surgery(<i>P</i><0.05). There were no postoperative complications in two groups.<p>CONCLUSION: PPV combined with ILM peeling without staining agent and flute needle drawing is effective in treating IMH, which is better than ILM-P group in both closure rate and BCVA improvement.
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AIM: To observe the clinical effects of intravitreal injection of triamcinolone acetonide ( TA ) before vitrectomy for retinal detachment associated with choroidal detachment. · METHODS: Totally 23 cases ( 23 eyes ) of retinal detachment associated with choroidal detachment in our hospital were treated by intravitreal injection of TA 4-5d before 23-Gauge micro-invasive vitrectomy combined with silicone oil injection. All the cases were followed up between 6 to 9mo. The anatomic retinal reattachment, visual acuity, intraocular pressure and postoperative complications were observed and analyzed. ·RESULTS: After the surgery, the visual acuity of all patients were improved, with 9 eyes better than 0. 3 (39%), and 18 eyes better than 0. 05 (78%). The BCVA at 1wk, 1 and 3mo and last follow up were different compared with before operations (P<0. 05). The mean intraocular pressure was 4. 02±1. 47mmHg before injection, 13.69±4. 68mmHg before operation (P<0. 05), and17.72±5.87 mmHg after operation (P<0.05). The retina of all patients treated were reattached 2wk post-operatively. The retinal reattachment rate after the primary surgery and the secondary surgery was 87% and 100%, respectively. Post-operative complications included 7 eyes of transient high intraocular pressure, occurred during 12-14d after operations and returned to normal after less glucocorticoid eye drops and giving IOP lowering drugs. There were no intraocular hemorrhage, iatrogenic retinal breaks, infections, or lens injuries. · CONCLUSION: Intravitreal injection of TA before vitrectomy for retinal detachment associated with choroidal could improve the clinical effects, and decrease the difficulty of surgery while the injection itself is pretty safe.
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Objective To evaluate the effect of breast blood oxygen functional imaging combined with mammography on breast cancer screening in women aged over 40 years.Methods A total of 10 076 cases of women in our hospital underwent breast blood oxygen functional imaging and mammography X -ray examination.The breast imaging report and data system (BI -RADS)III level of women performed on the biopsy pathology were used as the gold standard.The effect of different inspection methods were compared and analyzed.Results Among 10 076 cases,235 cases were diagnosed as BI -RADS,which was diagnosed by blood oxygen functional imaging system and a molybdenum target X -ray diagnosis of III.Thirteen cases with early breast cancer were diagnosed by needle biopsy.And 222 cases were diagnosed benign lesions.The sensitivity of the blood oxygen functional imaging system was 69.23% (9 /13)and 85.58% (190 /222), respectively.The sensitivity of molybdenum target X -ray was 76.92% (10 /13),and the specificity was 82.88% (184 /222).The sensitivity of combined detection was 100.0% (13 /13)and the specificity was 82.88% (184 /222).The accuracy index of combined molybdenum target X -ray (0.829)was significantly higher than that of single detection (0.548 and 0.598)(U =2.117,2.501,P <0.05).Conclusion Breast blood oxygen functional imaging instrument combined with molybdenum target examination could effectively improve the accuracy of diagnosis in breast cancer screening among women over 40 years.